What is H5N1 avian influenza, its symptoms, and how fatal can bird flu be?

Written by Aswathi Pacha
, Edited by Defined Desk | Kochi |

Up to date: July 22, 2021 8:15:59 am

On July 21, an 11-year-old boy died of H5N1 avian influenza in Delhi. That is the primary recorded loss of life because of the hen flu in India this yr. In January, hen flu was confirmed in a number of states with 1000’s of birds, together with migratory species, being discovered lifeless.

What’s hen flu?

Chicken flu or avian influenza is a illness attributable to avian influenza Sort A viruses discovered naturally in wild birds worldwide. The virus can infect home poultry together with chickens, geese, turkeys and there have been reviews of H5N1 an infection amongst pigs, cats, and even tigers in Thailand zoos.

Avian Influenza kind A viruses are categorized based mostly on two proteins on their surfaces – Hemagglutinin(HA) and Neuraminidase(NA). There are about 18 HA subtypes and 11 NA subtypes. A number of mixtures of those two proteins are doable e.g., H5N1, H7N2, H9N6, H17N10, and so on.

Chicken flu: An infection in people

There have been reviews of avian and swine influenza infections in people together with A(H1N1), A(H1N2), A(H5N1), A(H7N9), and so on. The primary report of human H5N1 an infection was in 1997 and presently, over 700 human circumstances of Asian Extremely Pathogenic Asian Avian Influenza A (HPAI) H5N1 virus have been reported to the World Well being Organisation from 16 nations. The an infection is lethal because it has a excessive mortality charge of about 60%.

The most typical route of virus transmission is direct contact — when an individual is available in shut contact with contaminated birds, both lifeless or alive.

People will also be affected if they arrive involved with contaminated surfaces or air close to the contaminated poultry. There isn’t a ample proof suggesting the unfold of the virus by means of correctly cooked meat.

Signs of avian influenza

In keeping with US CDC, the reported indicators and signs of avian influenza A virus infections in people have ranged from delicate to extreme influenza-like sickness.

* Fever, cough, sore throat, muscle aches, nausea, belly ache, diarrhea, vomiting
* Extreme respiratory sickness (e.g., shortness of breath, issue respiration, pneumonia, acute respiratory misery, viral pneumonia, respiratory failure)
* Neurologic modifications (altered psychological standing, seizures)

Threat teams

Youngsters and adults beneath 40 have been seen to be essentially the most affected and mortality was excessive in 10-19 years olds.

Chicken flu: Human-to-human transmission

AIIMS chief Dr. Randeep Guleria informed PTI that human-to-human transmission of the H5N1 virus was very uncommon and there was no have to panic. “The transmission of the virus from birds to people is uncommon and sustained human-to-human transmission of the H5N1 virus has not but been established and subsequently there isn’t a have to panic. However then folks working intently with poultry should take precautionary measures and keep correct private hygiene.”

A paper revealed in 2005 in The New England Journal of Drugs, investigated doable person-to-person transmission in a household cluster in Thailand and wrote that the “illness within the mom and aunt in all probability resulted from person-to-person transmission of this deadly avian influenza virus throughout unprotected publicity to the critically unwell index affected person.”

Dr Neeraj Nischal, an affiliate professor within the Division of Drugs at AIIMS, informed PTI that Avian influenza or hen flu is predominantly a zoonosis, and there’s no proof of sustained human-to-human transmission up to now.

“Though just a few remoted household clusters have been reported, transmission in these clusters might have occurred by means of frequent publicity and in uncommon conditions a really shut bodily contact; there isn’t a proof of human-to-human transmission by way of small-particle aerosols,” he added.

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